More than £165m has been raised since the first charity day in 1993.
Since1993, ICAP Charity Day has raised more than £160m.
A total of $700,000 will be donated to four charities.
The funds will go to 10 charities providing critical humanitarian aid.
Jefferies will donate 100% of net global trading commissions on October 10.
Doctors Without Borders/Médecins Sans Frontières (MSF) was the fifth non-profit to receive a donation.
The firm’s Doing Good Trading Day was held August 16.
All net global trading commissions on August 16 will support charities providing humanitarian aid in Hawaii.
Total £160m has been raised since the first Charity Day in 1993.